Parkinson's Disease | Parkinson's Research Facility at Harvard University

Harvard University At Harvard University’s McLean Hospital, we support the research of Dr. Ole Isacson whose research lab, The Stern Center for Neuroregeneration Research is using gene therapy to protect the most vulnerable neurons in PD models. Through this gene therapy, Dr. Isacson’s lab was able to protect the most vulnerable neurons in PD models. Dr. Isacson’s lab was able to generate neurons from dopamine cells that were transplanted.
These scientists also have made significant progress in studying a molecule called G-substrate, a phosphatase inhibitor. In human studies, they have found that transplanted fetal neurons can survive in patients for at least 14 years. All of these studies demonstrated new ways to protect and regenerate the dopamine system that produces the symptoms of Parkinson’s disease.

Michael Stern visits Dr. Ole Isacson, director of The Michael Stern Foundation Parkinson's Disease Research Center at Harvard University and McLean Hospital	Dr. Isacson stands outside the Mailman Research Center, location of his labs at McLean Hospital


			Dr. Paul Greengard's pioneering work in delineating how neurons communicate with one another in the brain earned him the 2000 Nobel Prize in Medicine or Physiology.