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What Sets Us Apart

TRAP Technology

The Michael Stern Parkinson’s Research Foundation has designed a research approach that we believe will greatly speed discovery of an effective new drug to prevent development of Parkinson’s disease — a medical condition caused by the death of dopamine-producing neurons. The current L-Dopa drug therapy attempts to replace dopamine that is lost due to the death of these cells, but this treatment has a positive effect for only a few years.

Our method applies the “TRAP Technology” that we originally developed in our laboratories to analyze and compare all of the proteins produced in two different kinds of dopamine-producing neurons in the brain. This approach will tell us why only a certain kind of dopamine-producing neurons die and will enable us to be the first to identify the proteins in dopamine-producing neurons that drive Parkinson’s disease, and may be targeted by a potential new drug to save these critical neurons.

The unique knowledge base and sophisticated technology the MSPRF research group has gained — led by the Nobel Laureate scientist, Dr. Paul Greengard — will allow us to precisely identify the protein targets responsible for the disease. As a result, we are optimistic that our PD research is on the fastest track to scientific discoveries that could defeat Parkinson’s disease. Furthermore, our research applies to 100% of PD patients, including those 5% whose disease is hereditary.

Our Scientists

Our scientists work synergistically and based on their understanding of how the disease ravages the brain, have developed many insights into how the devastating symptoms of Parkinson’s disease might be prevented or delayed. Their findings continue to be published in major scientific publications such as Nature, Cell, Science and the Proceedings of the National Academy of Sciences (PNAS).

To date, we have contributed over $46 million to Parkinson’s research. Significant accomplishments directly due to our funding include:

For additional information about our scientific studies, please contact us.